How much igf 1

Handbook of experimental pharmacology. Berlin: Springer-Verlag; 95 : — Lewitt M. Diabetes Res Clin Pract. Cohen P , Rosenfeld RG.

Curr Opin Pediatr. Diagnostic Systems Laboratories. Assay kit package insert. Nichols Institute Diagnostics. San Juan Capistrano : Nichols Institute; catalog no. J Clin Endocrinol Metab. Tan K , Baxter R. Growth Regul. J Endocrinol. National Committee for Clinical Laboratory Standards. Clin Endocrinol. Clin Endocrinol Oxf. Horm Metab Res.

Moore S , Stein WH. Methods in Enzymology. New York: Academic Press; vol 6 : — Anal Biochem. Rapid Commun Mass Spectr. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Sign In or Create an Account. Sign In. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents Subjects and Methods. Quarmby , V. Oxford Academic. Revision received:. Cite Cite V. Select Format Select format. Permissions Icon Permissions. A needle is used to draw blood from a vein in your arm or hand. Having a blood test with a needle carries some risks. These include bleeding, infection, bruising, and feeling lightheaded.

When the needle pricks your arm or hand, you may feel a slight sting or pain. Afterward, the site may be sore. Malnutrition or not eating fasting will affect your results. You don't need to get ready for this test. Be sure your healthcare provider knows about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don't need a prescription and any illegal drugs you may use. Some studies indicate a connection between these diseases and higher levels of IGF, insulin resistance, and inflammatory markers.

In adults, this test is most likely to be performed to check for pituitary gland disorders or tumors. It is not routinely given to people with diabetes. If your test results show higher or lower levels than the normal range, there could be several explanations, including:.

Your doctor will be able to offer an explanation based on a broader range of information. High levels of IGF may increase your risk for colorectal, breast, and prostate cancer, though no recent studies have reviewed this connection. Insulin that people use to treat type 2 diabetes may also increase the risk of certain cancers. Mecasermin Increlex is an artificial version of IGF. One of the potential side effects of mecasermin is hypoglycemia. If you have hypoglycemia, that means you have low blood glucose.

Research shows that IGF is capable of suppressing type 1 diabetes in mice. Some studies have shown that treatment with IGF may help control diabetes. While promising research exists, the relationship between IGF and diabetes is complicated. More research is necessary before doctors can use IGF to treat this complex disease. A variety of dietary supplements contain growth hormones, including IGF. Companies promote them for anti-aging, energy, and improving the immune system, among other claims.

If your child's results show lower than normal levels of IGF-1, it probably means he or she has a GH deficiency or insensitivity to GH. In a child, this may be caused by a genetic disorder or brain disease. Your child may benefit from treatment with GH supplementation.

GH supplementation is an injected medicine that contains manufactured human growth hormone. When GH deficiency is diagnosed and treated early, some children can grow several inches in the first year of treatment. Others grow less, and more slowly, but still benefit from treatment.

If your results show lower than normal IGF-1, it may be due to a normal age-related decrease in the hormone or other condition. Your provider may order more tests to help make a diagnosis.

Higher than normal levels of IGF-1 may mean gigantism in children or acromegaly in adults. Gigantism and acromegaly are most often caused by a tumor in the pituitary gland, a small organ in the base of the brain that controls many functions, including growth. If the disorder was not caused by a tumor, you or your child may need more tests.

Learn more about laboratory tests, references ranges, understanding results. Your provider may order other blood tests to help diagnose a GH disorder.

These include:. The information on this site should not be used as a substitute for professional medical care or advice.